Kinetic Parameter
Description
Reference
Rate constant for superoxide production
[S1]
Michaelis Menten constant for superoxide production
[S1]
kFe3
Rate constant for the conversion of superoxide to oxygen with simultaneous reduction of Fe3+ to Fe2+
[S2]
kH2O2
Rate constant for the production of hydrogen peroxide and oxygen from superoxide and H+ (non-enzymatic)
[S3]
kSOD
Rate constant for superoxide dismutase producing hydrogen peroxide from superoxide
[S3]
KmH2O2
Michaelis Menten constant for catalase induced conversion of H2O2 to H2O
[S4]
kcata
Rate constant for catalase induced conversion of H2O2 to H2O
[S4]
kFe1
Fenton reaction rate constant (hydrogen peroxide forming hydroxyl radical and anion with simultaneous conversion of Fe2+ to Fe3+)
[S2]
kinitLR
Rate constant for lipid peroxidation reaction by hydroxyl radicals, forming lipid radicals
[S5]
kLPO
Rate constant for the oxidation of lipid radicals
[S5]
kLR1
Rate constant for the formation of L* and LOOH from LH and LOO*
[S5]
kLRFe1
Rate constant for Fe2+ induced formation of LO* from LOOH
[S6]
kLRFe2
Rate constant for Fe3+ induced formation of LOO* from LOOH
[S6]
kfrLOO
Rate constant for LOO* fragmentation to alkane radical and aldehyde product
[S7]
kFe4
Rate constant for OH* induced formation of HO2* from H2O2
[S2]
kFe5
Rate constant for Fe3+ induced formation of HO* from H2O2
[S2]
kFe8
Rate constant for H2O2 formation from HO2*
[S2]
kFe9
Rate constant for the conversion of HO2* and H2O2 to H2O and OH*
[S2]
kFe6
Rate constant of Fe2+induced conversion of OH* to OH-
[S2]
kFe7
Rate constant for the conversion of OH* and HO2* to H2O and O2
[S2]
kdH2O
Dissociation rate of H2O to H+ and OH-
[S8]
KH2O
Association rate of H+ and OH- to H2O
[S8]
kAPX
Rate constant for APX induced conversion of Ascorbate to MDA
[S3]
KAPX
Michaelis Menten constant for APX induced conversion of ASC to MDA
[S3]
KAPXH
Michaelis Menten constant for APX induced conversion of H2O2 to H2O
[S3]
k_ASCH2O2
Rate constant for ASC and H2O2
[S3]
k_ASCO2
Rate constant for superoxide reacting with ascorbate
[S3]
kMDAR
Rate constant for molecular MDAR activity
[S3]
KMDARM
Michaelis Menten constant of MDAR for MDA
[S3]
KMDARN
Michaelis Menten constant of MDAR for NADPH
[S3]
k_MDAMDA
Apparent rate constant of MDA
[S3]
kDAR
Rate constant for molecular DAR activity
[S3]
KDAR
Michaelis Menten constant of DAR for DHA
[S3]
KDARG
Michaelis Menten constant of DAR for GSH
[S3]
k_DHAGSH
Apparent rate constant of GSH and DHA
[S3]
kGPxr
Rate constant of reduced GPx with H2O2
[S9]
kGPxo
Rate constant of oxidized GPx with GSH to form intermediate GSGPx
[S9]
kGSSG
Rate constant of GSGPx with GSH to recycle reduced Gpx
[S9]
kGR
Rate constant for molecular GR activity
[S3]
KGR
Michaelis Menten constant of GR for GSSG
[S3]
KGRN
Michaelis Menten constant of GR for NADPH
[S3]
kNAP
Rate constant for the conversion of NADP to NADPH
[S3]