SNPs

Function

Conclusions

Reference

TOPBP1 rs1051772

DNA repair

Decreased risk of RP in NSCLC patients

[90]

ATM rs1801516, ATM rs189037, ATM rs228590

DNA repair

Decreased risk of grade ≥ 3 RP in LC patients

[91] [92]

NEIL1 rs4462560, NEIL1 rs7402844

DNA repair

rs4462560 decreased risk of grade ≥ 2 RP in LC patients,

rs7402844 increased risk of grade ≥ 2 RP in LC patients

[93]

LIG4 rs1805388

DNA repair

Increased risk of grade ≥ 3 RP in LC patients

[94]

HIPK2 rs2030712

Apoptosis, proliferation, DNA repair, Inflammation

Increased risk of grade ≥ 2 RP in LC patients

[95]

TGFbeta1 rs1982073

Inflammation

Decreased risk of RP in NSCLC patients

[96]

IL4 rs2243250

Inflammation

Increased risk of grade ≥ 3 RP in LC patients

[97]

ITGB6 rs4665162

Inflammation

Increased risk of grade ≥ 2 RP in LC patients

[98]

BMP2 rs235768

BMP2 rs1980499

Inflammation

Increased risk of grade ≥ 2 RP in LC patients

[99]

ATG16L2 rs10898880

Autophagy

Increased risk of RP in NSCLC patients

[100]

PAI-1 rs7242

Plasmin system inhibition

Increased risk of grade ≥ 3 RP in LC patients

[101]