SNPs | Function | Conclusions | Reference |
TOPBP1 rs1051772 | DNA repair | Decreased risk of RP in NSCLC patients | [90] |
ATM rs1801516, ATM rs189037, ATM rs228590 | DNA repair | Decreased risk of grade ≥ 3 RP in LC patients | [91] [92] |
NEIL1 rs4462560, NEIL1 rs7402844 | DNA repair | rs4462560 decreased risk of grade ≥ 2 RP in LC patients, rs7402844 increased risk of grade ≥ 2 RP in LC patients | [93] |
LIG4 rs1805388 | DNA repair | Increased risk of grade ≥ 3 RP in LC patients | [94] |
HIPK2 rs2030712 | Apoptosis, proliferation, DNA repair, Inflammation | Increased risk of grade ≥ 2 RP in LC patients | [95] |
TGFbeta1 rs1982073 | Inflammation | Decreased risk of RP in NSCLC patients | [96] |
IL4 rs2243250 | Inflammation | Increased risk of grade ≥ 3 RP in LC patients | [97] |
ITGB6 rs4665162 | Inflammation | Increased risk of grade ≥ 2 RP in LC patients | [98] |
BMP2 rs235768 BMP2 rs1980499 | Inflammation | Increased risk of grade ≥ 2 RP in LC patients | [99] |
ATG16L2 rs10898880 | Autophagy | Increased risk of RP in NSCLC patients | [100] |
PAI-1 rs7242 | Plasmin system inhibition | Increased risk of grade ≥ 3 RP in LC patients | [101] |