| Mohs | Curaderm |
| Surgical knife | Cream |
| Invasive | Topical, effective transdermal delivery |
| Necrosis | Apoptosis |
| Experienced operators and ancillary support | Self-administration |
| Anaesthetics | Occlusive dressing |
| Removal of cancer cells and normal tissue | Removal of cancer cells only |
| Skin flaps or grafts or reconstructive surgery | Natural healing |
| Scar tissue | No scar tissue |
| 95% success | 95% success |
| Low recurrence rates | Low recurrence rates |
| Long waiting time | No waiting time |
| Outpatient, same day treatment | 2 to 14 weeks treatment |
| Good cosmetic outcome | Excellent cosmetic outcome |
| Expensive | Economical |