Variable

Total

(n = 61)

Low miRNA-155

(n = 44)

High miRNA-155

(n = 17)

T

p

Age (years)

Mean ± SD

45.61 ± 14.52

39.26 ± 12.43

47.73 ± 16.74

0.58

Median

43

30

42

Range

18 - 55

18 - 53

20 - 55

TLC (×10³/mm³)

Mean ± SD

52.2 ± 23.21

32.7 ± 21.54

71.6 ± 29.01

4.56

0.002

Median

40

32

65

Range

0.9 - 250

0.9 - 125

1.2 - 250

Hb (gm/dL)

Mean ± SD

9.2 ± 2.77

9.3 ± 2.37

9.2 ± 1.91

1.11

0.41

Median

9.3

9.3

9.1

Range

5.5 - 15

5.5 - 15

6.1 - 13.5

Platelets (×10³/mm³)

Mean ± SD

83.63 ± 27.42

80.74 ± 25.44

86.52 ± 26.21

1.13

0.27

Median

75

72

78

Range

5 - 460

5 - 430

7.0 - 460

PB Blasts (%):

Mean ± SD

47.5 ± 15.74

38.16 ± 12.39

56.76 ± 18.37

3.89

0.006

Median

45

43

60

Range

0 - 80

0 - 75

0 - 80

BM blasts (%):

Mean ± SD

79.18 ± 13.59

70.83 ± 13.53

87.54 ± 13.81

3.47

0.008

Median

70

65

78

Range

20 - 98

20 - 98

40 - 98

FAB subtype

M2

14 (31.8%)

4 (23.5%)

0.48

M4

13 (29.6%)

5 (29.4%)

M5

17 (38.6%)

8 (47.1%)

Cytogenetics

Favourable

9 (20.5%)

1 (5.9%)

0.007

Intermediate

32 (72.7%)

2 (11.8%)

Poor

3 (6.8%)

14 (82.3%)

Response to treatment

CR

42 (68.9%)

38 (86.4%)

4 (23.5%)

0.004

No CR

19 (31.1%)

6 (13.6%)

13 (76.5%)