Study | Tumor Type | Number | Study Design | Injection Site | Dose ml | Waiting Time | Laparoscopic | Indices |
Cai et al. [13] | Colorectal | 60 | RCT | 4-quadrant region around the mass | 1 | 10 min | No | ①④⑨ |
Zhang et al. [17] | Rectal | 87 | NRCT | Around the submucosa of the rectum | 5 | 30 min | In 96% cases | ①④ |
Wang et al. [18] | Rectal | 152 | NRCT | 3 points around the submucosal layer of mass | 0.5 | 1 day | in 97% cases | ①②⑧ |
Yang et al. [12] | Colorectal | 65 | RCT | 4 - 6 points around the mass | 0.15 - 0.25 | 10 min | Yes | ①②③④ |
Zhang et al. [16] | Colorectal | 53 | NRCT | 4 points around the submucosal layer of mass | 0.15 - 0.25 | 1 - 3 day | Yes | ①②③④⑧ |
Wang et al. [15] | Colorectal | 54 | NRCT | 4 points around the submucosal layer of mass | 1 | 10 min | Yes | ①⑤⑦⑧ |
Wang et al. [14] | Colorectal | 470 | NRCT | 4 - 6 points around the mass | 1 | 30 min | No | ①②⑤⑦ |