Variables

18 - 30 years old

N = 136

31 - 49 years old

N = 138

50 - 68 years old

N = 44

Normal/CIN-1 (n = 55)

CIN 2-3/Cancer (n = 81)

Normal/CIN-1 (n = 56)

CIN 2-3/Cancer (n = 82)

Normal/CIN-1 (n = 20)

CIN 2-3/Cancer (n = 24)

Menopause (Mean ± SD)

-

-

46.7 (0.6)*

42.5 (0.7)*

46.5 (7.5)*

50.0 (2.8)*

Number Pregnancies (Mean ± SD)

1.6 (1.5)*

2.3 (1.5)*

3.2 (2.0)

3.7 (2.2)

4.1 (2.1)

4.2 (3.1)

Pack-year smoked (Mean ± SD)

3.4 (4.5)

5.9 (6.7)

12.0 (10.6)*

19.2 (15.9)*

33.0 (41.5)

22.0 (26.0)

Menarche

≤12 years

28 (50.9)

50 (61.7)

39 (69.6)

52 (63.4)

12 (60.0)

14 (58.3)

>12 years

27 (49.1)

31 (38.3)

17 (30.4)

30 (36.6)

08 (40.0)

10 (41.7)

Age at sexual onset

≤16 years

35 (63.6)

61 (75.3)

15 (26.8)*

39 (47.6)*

05 (25.0)

07 (29.2)

>16 years

20 (36.4)

20 (24.7)

41 (73.2)

43 (52.4)

15 (75.0)

17 (70.8)

Parity

0 - 1

39 (70.9)

39 (48.1)

16 (28.6)

16 (19.5)

02 (10.0)

06 (25.0)

>1

16 (29.1)*

42 (51.9)*

40 (71.4)

66 (80.5)

18 (90.0)

18 (75.0)

Number of Abortions

0 - 1

49 (89.1)

72 (88.9)

47 (83.9)

64 (78.0)

14 (70.0)

14 (58.3)

>1

06 (10.9)

09 (11.1)

9 (16.1)

18 (22.0)

06 (30.0)

10 (41.7)

Number of Sexual Partners

1 - 2

21 (38.2)

25 (30.9)

21 (37.5)

15 (18.3)

11 (55.0)

09 (37.5)

3 - 4

16 (29.1)

29 (35.8)

13 (23.2)*

33 (40.2)*

03 (15.0)

10 (41.7)

≥5

18 (32.7)

27 (33.3)

22 (39.3)*

34 (60.7)*

06 (30.0)

05 (20.8)

Oral Contraceptive

Current use

38 (69.1)

57 (70.4)

29 (51.8)

42 (51.2)

6 (30.0)*

13 (54.2)*

Former use

07 (12.7)

17 (21.0)

17 (30.3)

27 (32.9)

9 (45.0)

4 (16.7)

Never use

10 (18.2)

07 (8.6)

10 (17.9)

13 (15.9)

5 (25.0)

7 (29.2)

Duration of contraceptive use

0

10 (18.2)

07 (8.6)

11 (19.6)

14 (17.1)

05 (25.0)

07 (29.2)

1 - 60

28 (50.9)

38 (47.0)

16 (28.6)

31 (37.8)

06 (30.0)

08 (33.3)

≥60

17 (30.9)*

36 (44.4)*

29 (51.8)

37 (45.1)

09 (45.0)

09 (37.5)

Tobacco Smoking

Current smoker

10 (18.2)

20 (24.7)

14 (25.0)*

39 (47.6)*

4 (20.0)

8 (34.8)

Former smoker

04 (7.3)

14 (17.3)

13 (31.2)

18 (22.0)

9 (45.0)

8 (34.8)

Never smoke

41 (74.5)

47 (58.0)

29 (51.8)

25 (30.5)

7 (35.0)

7 (30.4)

Duration of tobacco smoking

≤15

14 (100)

30 (88.2)

10 (37.0)

11 (19.3)

04 (30.8)

06 (37.5)

>15

0 (0.0)

04 (11.8)

17 (63.0)

46 (80.7)

09 (69.2)

10 (62.5)