| Toxicity | ≥G3 | P value | ||
| A | B | |||
| Hematological toxicities | Anemia | 4 [13.3] | 2 [6.7] | NS |
| Neutropenia | 8 [26.7] | 1 [3.3] | 0.03 | |
| Thrombocytopenia | 0 [0] | 0 [0] | NS | |
| GIT toxicities | Diarrhea | 7 [23.3] | 0 [0] | 0.01 |
| Anorexia | 6 [20] | 0 [0] | 0.02 | |
| Nausea | 2 [6.7] | 0 [0] | NS | |
| Vomiting | 0 [0] | 1 [3.3] | NS | |
| Dysphagia | 2 [6.7] | 0 [0] | NS | |
| Mucositis | 6 [20] | 0 [0] | 0.03 | |
| Neurotoxicity | 0 [0] | 0 [0] | NS | |
| Weight loss | 1 [3.3] | 0 [0] | NS | |
| Fatigue | 2 [6.7] | 0 [0] | NS | |
| Hand foot syndrome | 0 [0] | 0 [0] | NS | |