| Animal | Weight/age | Induction mode | Induction time | Related pathological changes | biochemistry |
| Rabbit and mice |
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| male rabbits [47] | 2 - 2.5 kg | vitD2 (25,000 IU/4 days per week) | 8weeks | Fibrosis/calcification, inflammatory activation, atherosclerotic changes | Calcium phosphate product, total cholesterol and SCR↑ |
| male C57BL/6J mice [52] | 16 weeks age | injection of 100 µL VD3 (5.5 × 105 U/kg) once daily for three consecutive times | 3 days + 6 Weeks | medial arterial calcification | VD3↑↑↑, BUN and ALT↑, Tissue metabolism disorder |
| male C57BL/6 mice [55] | 6 weeks age | 0.2% adenine in chow+intraperitoneally injected VitD (8.75 mg/kg/day) | adenine 3 weeks, vitD 10 day | calcification | BUN, SCR and Ca2+ ↑↑↑, P↑↑ |
| Rat |
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| male rats [145] | 8 weeks old/250 g | fed high-adenine (0.75%) + high phosphate diet (1.5%) + normal rat chow | 7 weeks + 2 weeks | calcification, ossification, inflammation | SCR and P↑↑↑, PTH, Hyperparathyroidism |
| male rats [146] | 8 weeks old/250 g | 5/6Nx + HP (P = 2.0%) | 8, 12, 16 weeks | calcification（[Ca5(PO4)3(OH)]）、glycosylation | SCR, BUN and 24 hour urine protein↑, PTH↑↑↑, P↑↑ |
| Male Wistar rats [147] | 200 - 250 g | vitD: 300,000 IU/kg, CH: 2%, PH: 1.5% | 4, 8, 12 weeks | Ca, TC, Lipid vacuoles (most in 2 groups), Ca deposition in aortic valve lobules | LDL/HDL↑, Hypertrophic neointima |
| vitD: 150,000 IU/kg, CH: 1%, PH: 0.75% | LDL/HDL↑, Maximum heart mass, maximum AVPG | ||||
| vitD: 300,000 IU/kg, PH: 1.5% | rigid spine | ||||
| vitD: 300,000 IU/kg, CH: 2% | rigid spine , Hypertrophic neointima | ||||