Company | Target products | Classes | Products and market | Commercial interest |
BASF http://www.corporate.basf.com/ | Enzymes | Amylase Hydratase | Acidophilic gluco amylase | Food industry, aiding with the digestion of starch |
Bioresearch Italia, SpA (Italy) | Anti-infectives | Vancomycin | Dalbavancin | Development of human gene targeted therapeutics and novel anti-infective |
B.R.A.I.N http://www.brain-biotech.de/ | Bioactive peptides and enzymes for pharmaceuticals and agrochemicals | N.D. | Nitrile hydratases Cellulases | Degussa AG Partnership for the industrial processe |
Cubist pharmaceuticals https://www.merck.com/ | Anti-infectives | N.D. | N.D. | Various commercial relationships. Variety of products in Stage I, II and III trials |
Diversa http://www.diversa.com/ | Enzymes | Nitrilase Glycosidase Phytase | Discovery of 100 novel nitrilases Production of Lipitor Pyrolasee 160 and Pyrolasee 200; Phyzymee XP | Drug, lowering cholesterol levels Broad spectrum b-mannanase and b-glucanase added to animal feed to break down indigestible phytate in grains and oil s eeds to release digestible |
| Biometabolites | Fluorescent protein | Discovery Pointe Green-F P* and Cyan-FP* | Novel green and cyan flu orescent proteins for potential u se in drug discovery, ommercial screening and academic research |
Diversa and Invitrogen https://www.thermofisher.cn/cn/zh/home.html | Enzymes | DNA polymerase | hermal Acee and Replicasee DNA for research and diagnostics | Research and diagnostics |
EMetagen | Enzymes; antibiotics; small active molecules | Polyketides | eMetagen Gene and Pathway Banks eLarge clone DNA libraries encoding biosynthetic pathways for 5000 to 20,000 secondary metabolites | Food, agriculture, research and other commercial applications Pharmaceuticals: antimicrobial, anticancer and other bioactive properties |
Kosan Technology http://www.kosan.com/ | Antibioti cs | Polyketides | Adriamycin, Erythromycin, Meva-cor, Rapamycin, Tacrolimus (FK506), Tetracycl ine, Rapamyc in, | Therapeutic drugs |
Genencor http://www.genencor.com/ | Enzymes | Lipase, Protease | Washing powder and alkaline tolerant protease. | Cleaning industry |
Libragen http://www.libragen.com/ | Antibiotics and biocatalysis for pharmace uticals | N.D. | Anti-infective and antibiotic discovery Biocatalysis discovery for pharmaceuticals (partnership with Synkem) | Medicine; synthesis of pharmaceuticals |
Prokaria http://www.prokaria.is/ | Enzymes | Rhamnosidase b-1,6 Gluconase; Single stranded DNA ligase | Food and agricultural industry | Food industry |