Time

(Hours)

G1 (250 mg/kg)

G2 (500 mg/kg)

G3 (10 mg/kg

indomethacine)

G4 (un-treated control

1

0.53 ± 0.12 NS

0.48 ± 00.5 NS

0.73 ± 00.19 NS

01.00 ± 00.28

2

0.78 ± 0.22**

0.35 ± 00.08**

1.10 ± 00.48 NS

01.70 ± 0.19

4

0.65 ± 0.16**

0.25 ± 014***

0.67 ± 0.12***

01.42 ± 0.0

6

0.63 ± 0.21 NS

0.35 ± 00.22*

0.63 ± 0.08**

0.97 ± 00.1

24

0.18 ± 0.12 NS

0.20 ± 0.90*

0.2 ± 0.23 NS

0.65 ± 00.1