Exposure to: | Number of cells ×106 | NL/АМ count ratio | ||
total | neutrophil leukocytes (NL) | alveolar macrophages (АМ) | ||
24 hours after the intratracheal instillation of NiO-NPs and Mn3O4 + NPs | ||||
Me-NPs | 9.6 ± 1.6* | 7.17 ± 1.24* | 2.3 ± 0.43 | 3.44 ± 0.62* |
Me-NPs after 4 weeks BPC administration | 5.7 ± 1.49 | 3.36 ± 1.38*+ | 2.3 ± 0.29 | 1.46 ± 0.54*+ |
Water after 4 weeks BPC administration | 3.8 ± 0.75 | 0.67 ± 0.21 | 3.09 ± 0.64 | 0.23 ± 0.07 |
Water (control) | 3.8 ± 0.9 | 0.34 ± 0.12 | 3.4 ± 0.86 | 0.12 ± 0.05 |
24 hours after the intratracheal instillation of PbO-NPs + CuO-NPs + ZnO-NPs | ||||
Me-NPs | 7.93 ± 0.62* | 5.86 ± 1.52* | 2.07 ± 0.21 | 2.83 ± 0.77 |
Me-NPs after 4 weeks BPC administration | 3.30 ± 0.53*+ | 1.47 ± 0.36+* | 1.82 ± 0.40 | 1.11 ± 0.30+ |
Water after 4 weeks BPC administration | 2.18 ± 0.41 | 1.20 ± 0.35* | 0.98 ± 0.25 | 1.59 ± 0.55* |
Water (control) | 1.40 ± 0.07 | 0.094 ± 0.029 | 1.30 ± 0.07 | 0.075 ± 0.024 |