Characteristics | Univariate | Multivariate |
aOR (CI95%) | aOR (CI95%) | |
Current age (years) |
|
|
[50 - 59] | Ref |
|
[60 - 69] | 1.90 (0.95 - 3.82) | 1.98 (0.67 - 5.87) |
≥70 | 5.37 (2.06 - 14.00) | 5.21 (1.44 - 18.88) |
Age at ART initiation (years) |
|
|
<50 | Ref |
|
≥50 | 0.62 (0.21 - 1.86) |
|
Sex |
|
|
Male | Ref |
|
Female | 1.05 (0.54 - 2.03) | 0.79 (0.31 - 2.04) |
WHO stage at inclusion |
|
|
I | Ref |
|
II | 1.14 (0.44 - 2.97) | 1.2 (0.31 - 4.91) |
III | 1.59 (0.67 - 3.79) | 1.95 (0.52 - 7.28) |
IV | 3.42 (1.08 - 10.83) | 4.13 (0.62 - 27.55) |
Nadir TCD4 lymphocyte counts (elements/mm3) |
|
|
<200 | Ref |
|
≥200 | 1.41 (0.73 - 2.72) |
|
Duration under ART (months) |
|
|
<120 | Ref |
|
120 - 240 | 0.55 (0.23 - 1.28) | 0.24 (0.06 - 1) |
>240 | 1.50 (0.48 - 4.75) | 0.34 (0.05 - 2.15) |
Duration of TDF exposure |
|
|
<10ans | Ref |
|
≥10ans | 20.91 (8.62 - 50.73) | 29.21 (9.5 - 89.76) |
Body mass index |
|
|
Normal | Ref |
|
Underweight | 1.96 (0.69 - 5.53) |
|
Overweight/obesity | 0.61 (0.29 - 1.28) |
|
Sensory disorders |
|
|
No | Ref |
|
Yes | 1.18 (0.60 - 2.33) | 3.07 (0.61 - 15.39) |
MNA |
|
|
Normal | Ref |
|
Nutritional disorder | 3.49 (2.36 - 5.16) | 3.84 (2.30 - 6.41) |
Comorbidities |
|
|
<1 | Ref |
|
1 - 2 | 0.78 (0.35 - 1.71) |
|
≥2 | 0.90 (0.35 - 2.28) |
|
Charlson comorbidity index |
|
|
<1 | Ref |
|
1 - 2 | 1.06 (0.46 - 2.44) |
|
≥3 | 1.08 (0.44 - 2.68) |
|
Polypharmacy |
|
|
≤4 | Ref |
|
≥5 | 1.39 (1.12 - 1.74) | 1.53 (1.10 - 2.12) |