Characteristics

Univariate

Multivariate

aOR (CI95%)

aOR (CI95%)

Current age (years)

[50 - 59]

Ref

[60 - 69]

1.90 (0.95 - 3.82)

1.98 (0.67 - 5.87)

≥70

5.37 (2.06 - 14.00)

5.21 (1.44 - 18.88)

Age at ART initiation (years)

<50

Ref

≥50

0.62 (0.21 - 1.86)

Sex

Male

Ref

Female

1.05 (0.54 - 2.03)

0.79 (0.31 - 2.04)

WHO stage at inclusion

I

Ref

II

1.14 (0.44 - 2.97)

1.2 (0.31 - 4.91)

III

1.59 (0.67 - 3.79)

1.95 (0.52 - 7.28)

IV

3.42 (1.08 - 10.83)

4.13 (0.62 - 27.55)

Nadir TCD4 lymphocyte counts (elements/mm3)

<200

Ref

≥200

1.41 (0.73 - 2.72)

Duration under ART (months)

<120

Ref

120 - 240

0.55 (0.23 - 1.28)

0.24 (0.06 - 1)

>240

1.50 (0.48 - 4.75)

0.34 (0.05 - 2.15)

Duration of TDF exposure

<10ans

Ref

≥10ans

20.91 (8.62 - 50.73)

29.21 (9.5 - 89.76)

Body mass index

Normal

Ref

Underweight

1.96 (0.69 - 5.53)

Overweight/obesity

0.61 (0.29 - 1.28)

Sensory disorders

No

Ref

Yes

1.18 (0.60 - 2.33)

3.07 (0.61 - 15.39)

MNA

Normal

Ref

Nutritional disorder

3.49 (2.36 - 5.16)

3.84 (2.30 - 6.41)

Comorbidities

<1

Ref

1 - 2

0.78 (0.35 - 1.71)

≥2

0.90 (0.35 - 2.28)

Charlson comorbidity index

<1

Ref

1 - 2

1.06 (0.46 - 2.44)

≥3

1.08 (0.44 - 2.68)

Polypharmacy

≤4

Ref

≥5

1.39 (1.12 - 1.74)

1.53 (1.10 - 2.12)