| Predictive factors for finding of cancer | ||||||||||
| Study | #HGPIN patients re-biopsied | % of total HGPIN patients | Bx time frame | Percentage positive for cancer | Age | PSA | PSAD | PSAV | Number Cores of HGPIN | Unilateral or bilateral HGPIN |
| Herawi [9] | 791 | NS | ≤1 yr | 18% | No | NS | NS | NS | No | NS |
| Lee [15] | 328 | 45% | ≤2.56 yr | 36% | NS | NS | NS | NS | Yes | Yes |
| Roscigno [18] | 262 | NS | 3 - 30 mo | 32% | Yes | Yes | NS | NS | Yes | NS |
| Schlesinger [11] | 204 | NS | <14 mo | 23% | NS | NS | NS | NS | NS | NS |
| O’Dowd [16] | 4902 | 27% | ≤1 yr | 23% | No | Yes | NS | NS | NS | NS |
| Merrimen [12] | 564 | 44% | ≤1.91 yr | 27% | Yes | NS | NS | NS | Yes | NS |
| Taneja [19] | 1185 | 100% | 1 - 3 years | 32% | Yes | Yes | NS | Yes | NS | NS |
| Current study | 362 | 64% | 7 mo median | 37% | No | Yes | Yes | NS | No | No |