Primi

N = 22

N (%)*

Second

N = 21

N (%)*

Third

N = 37

N (%)

Fourth

N = 22

N (%)

>Fourth

N = 59

N (%)

p-value˚

Personal barriers

Unawareness of the injection method.

9 (40.9)

13 (61.9)

14 (37.8)

9 (40.9)

21 (35.6)

0.324

Unawareness of insulin dose control method.

12 (54.5)

16 (76.2)

21 (56.8)

9 (40.9)

16 (27.1)

0.001

Doubt about the efficacy of insulin.

2 (9.1)

3 (14.3)

6 (16.2)

2 (9.1)

12 (20.3)

0.650

Fear of (needles, pain at the injection site).

6 (27.3)

8 (38.1)

14 (37.8)

12 (54.5)

26 (44.1)

0.428

Preference for other treatment methods over insulin.

13 (59.1)

12 (57.1)

17 (45.9)

12 (54.5)

37 (62.7)

0.609

Past personal experience of insulin-related complications.

0 (0.0)

0 (0.0)

4 (10.8)

3 (13.6)

14 (23.7)

0.014

Treatment plan complexity.

5 (22.7)

6 (28.6)

7 (18.9)

3 (13.6)

13 (22.0)

0.807

Relying on others to take insulin.

5 (22.7)

3 (14.3)

10 (27.0)

3 (13.6)

7 (11.9)

0.350

Religious beliefs.

2 (9.1)

3 (14.3)

1 (2.7)

2 (9.1)

2 (3.4)

0.335

Lack of confidence in doctors’ opinions.

2 (9.1)

0 (0.0)

3 (8.1)

0 (0.0)

3 (5.1)

0.432

Forgetfulness.

9 (40.9)

7 (33.3)

11 (29.7)

11 (29.7)

22 (37.3)

0.902

Family (social) barriers

Lack of family support for taking insulin injections.

3 (13.6)

1 (4.8)

8 (21.6)

2 (9.1)

10 (16.9)

0.430

Feeling Stigmatized.

1 (4.5)

2 (9.5)

4 (10.8)

1 (4.5)

3 (5.1)

0.772

Past family experience of insulin-related complications.

6 (27.3)

5 (23.8)

7 (18.9)

8 (36.4)

13 (22.0)

0.627

Side effects barriers

Fear of hypoglycaemia.

14 (63.6)

11 (52.4)

24 (64.9)

15 (68.2)

31 (52.5)

0.577

Fear of weight gain.

13 (59.1)

10 (47.6)

15 (40.5)

13 (59.1)

31 (52.5)

0.571

Fear of allergic reactions at the injection site.

7 (31.8)

9 (42.9)

13 (35.1)

10 (45.5)

27 (45.8)

0.725

Misconceptions about insulin injections

Insulin may lead to stillbirth.

1 (4.5)

1 (4.8)

7 (18.9)

4 (18.2)

12 (20.3)

0.252

Insulin is addictive; the injection will continue for life.

2 (9.1)

5 (23.8)

9 (24.3)

8 (36.4)

18 (30.5)

0.266

Insulin causes aging.

0 (0.0)

1 (4.8)

3 (8.1)

4 (18.2)

8 (13.6)

0.220

Insulin negatively affects sexual desire.

0 (0.0)

4 (19.0)

3 (8.1)

5 (22.7)

8 (13.6)

0.146

Work-related barriers

Long working hours.

2 (9.1)

3 (14.3)

6 (16.2)

6 (27.3)

6 (10.2)

0.349

Irregular eating times during working hours.

2 (9.1)

3 (14.3)

7 (18.9)

5 (22.7)

7 (11.9)

0.635

Lack of privacy during injection.

2 (9.1)

3 (14.3)

5 (13.5)

6 (27.3)

3 (5.1)

0.092