Parameter

Values

Total number of compounds in database (D)^a

550

Total number of actives in database (A)

50

Total number of hit compounds from the database (Ht)^b

57

Total number of active compounds in hit list (Ha)

49

%Yield of actives (%Y) [(Ha/Ht) × 100]

85.96

%Ratio of actives (%R) [Ha/A] × 100]

98.00

False negatives [A − Ha]

1

False positives [Ht − Ha]

8

Goodness of hit (GH)^c

0.876