| Criterion according to | |
| Bhatt et al. [7] | Zou et al. [8] |
| Source of data: | Purpose of data coverage: |
| Primary (information derived from experiments) | Comprehensive (different types of data from numerous species) |
| Secondary (databases derived from primary) | Specialized (specific types of data from specific organism) |
| Type of data: | Type of data covered: |
| Sequence data | DNA |
| Structure | RNA |
| Literature | Protein |
| Pathway | Expression |
| Chemical | Pathway |
| Enzyme | Disease |
| Disease | Nomenclature |
| Domain | Literature |
| Structural classification of protein | Standard and oncology |
| Genome |
|
| Database design: | Curation level: |
| Object-oriented (information is characterized in the form of objects) | Primary (raw data as archival repository) |
| Relational (comprehensive tables of data) | Secondary or derivative (curated data as added value) |
| Composite databases: | Curation method: |
| Combination of primary databases sources, making the query more efficient | Expert-curated Community curated (collectively and collaboratively) |