|
| Total n = 68 Number (%/IQR) | Survivors n = 54 Number (%/IQR) | Non-survivors n = 14 Number (%/IQR) | P-value* |
| Gender |
|
|
|
|
| Male | 40 (58.82) | 33 (61.11) | 7 (50) | 0.5468 |
| Age |
|
|
|
|
| ≤5 years old | 45 (66.18) | 37 (68.52) | 8 (57.14) | 0.5288 |
| Clinical manifestations |
|
|
|
|
| Fever > 39˚C | 42 (61.76) | 28 (51.85) | 14 (100) | 0.0005 |
| time of fever lasting (days) | 3 (1 - 22) | 4 (1 - 22) | 3 (1 - 17) | 0.43 |
| Respiratory symptoms | 30 (44.12) | 23 (42.59) | 7 (50) | 0.5586 |
| Convulsion | 48 (33.30) | 36 (30.30) | 12 (36.70) |
|
| Less than 3 times | 24 (64.71) | 18 (66.67) | 6 (57.14) | 0.5415 |
| More than 3 times | 24 (35.29) | 18 (33.33) | 6 (42.86) | |
| Headache | 12 (17.65) | 11 (20.37) | 1 (7.14) | 0.4351 |
| Vomiting | 22 (32.35) | 16 (29.63) | 6 (42.86) | 0.3559 |
| Fatigue | 19 (27.94) | 17 (31.48) | 2 (14.29) | 0.3186 |
| ADOC | 36 (52.90) | 22 (40.7) | 14 (100) | <0.0001 |
| Cardiac arrest | 6 (8.82%) | 1 (1.85) | 5 (35.7) | 0.001 |
| Routine blood test |
|
|
| |
| Leukocyte (×109/L) | 8.55 (2.4 - 29.6) | 8.5 (2.4 - 29.6) | 8.8 (3.2 - 21.7) | 0.8837 |
| Lymphocytes (×109/L) | 1.89 (0.32 - 16.01) | 2.03 (0.32 - 16.01) | 1.55 (0.38 - 5.1) | 0.4105 |
| Monocyte (×109/L) | 0.58 (0.06 - 3.45) | 0.6 (0.15 - 3.45) | 0.38 (0.06 - 0.97) | 0.08 |
| Comprehensive metabolic panel |
|
|
| |
| Serum |
|
|
|
|
| ALT (U/L) | 33 (9 - 7304) | 28.5 (9 - 1885) | 70 (13 - 7304) | 0.0074 |
| AST (U/L) | 69 (19 - 16,770) | 51.5 (19 - 1681) | 176 (43 - 16,770) | <0.0001 |
| CK (U/L) | 246 (28 - 16,549) | 204 (28 - 16,549) | 669 (86 - 9350) | 0.0069 |
| LDH (U/L) | 357 (197 - 11,962) | 322 (197 - 2495) | 870 (332 - 11,962) | <0.0001 |
| CRP (mg/dL) | 5 (0 - 141.95) | 3.78 (0 - 141.95) | 11.35 (2.43 - 128.06) | 0.037 |
| Lactate(mmol/L) | 1.7 (0.5 - 11.1) | 1.6 (0.5 - 6.4) | 2.45 (1 - 11.1) | 0.0036 |
| CSF |
|
|
|
|
| Protein (g/L) | 0.44 (0.12 - 34.5) | 0.34 (0.12 - 12.4) | 1.895 (0.12 - 34.5) | <0.0001 |
| Leukocyte (×106/L) | 6 (0 - 350) | 6 (0 - 350) | 9 (1 - 28) | 0.919 |
| Pathogenetic test |
|
|
| |
| FA | 43 (63.2) | 35 (64.8) | 8 (57.1) | 0.7569 |
| FB | 25 (36.8) | 19 (35.2) | 6 (42.9) | |
| Treatments |
|
|
| |
| Oseltamivir | 68 (100.00) | 54 (100.00) | 14 (100.00) | 1 |
| Gammaglobulin | 68 (100.00) | 54 (100.00) | 14 (100.00) | 1 |
| Methylprednisolone | 68 (100.00) | 54 (100.00) | 14 (100.00) | 1 |
| Ventilator-assisted ventilation | 24 (35.29) | 12 (22.22) | 12 (85.71) | <0.0001 |