Mean | Start (pre-CAI) | 3 months | 6 months | 12 months Final | % improvement start-end | p-value* | |
MF in 12 h | 7.0 ± 0.6 | 4.1 ± 0.4 | 3.0 ± 0.1 | 3.0 ± 0.6 | 56.4% | 0.001* | |
AIMS | 16 ± 0.6 | 5.8 ± 0.7 | 6.2 ± 1.0 | 4.2 ± 0.5 | 74.0% | 0.001* | |
% in S & E | 60% | 70% | 70% | 70% | 16.7% | <0.001* | |
NPI | 16 ± 0.6 | 7.8 ± 0.8 | 6.2 ± 1.0 | 8 ± 0.6 | 49.9% | 0.001* | |
NMSS | 77.8 ± 5.2 | 64 ± 4.4 | 63 ± 2.2 | 63 ± 1.6 | 18.8% | 0.017* | |
HADS | A | 9.0 ± 0.6 | 7.0 ± 1.3 | 7.0 ± 0.6 | 7.0 ± 0.6 | 21.7% | 0.016* |
D | 17.3 ± 2.4 | 16.2 ± 8 | 14.2 ± 1.2 | 12.9 ± 0.5 | 32.1% | 0.001* |