Estimable parameter

Experimental groups of animals

IV

Solution NiCl2 (5%)

V

MND (5.0 g・L−1) + solution NiCl2 (5%)

VI

MND (10.0 g・L−1) + solution NiCl2 (5%)

Free interstitial space

13.9 ± 0.31

7.8 ± 0.24*

7.1 ± 0.23*

Blood vessels

3.0 ± 0.15

1.5 ± 0.09*

1.4 ± 0.11*

Lymphocytes

1.8 ± 0.12

0.7 ± 0.08*

0.3 ± 0.05*

Neutrophils

1.0 ± 0.09

0.4 ± 0.06*

0.3 ± 0.05*