Group | Treatment of experimental skin area once a day during 10 days | Treatment of intact skin area on 12 |

I | 2% solution of CoCl | 2% solution of CoCl |

II | MND 5.0 g・L 2% solution of CoCl | 2% solution of CoCl |

III | MND 10.0 g・L 2% solution of CoCl | 2% solution of CoCl |

IV | 5% solution of NiCl | 5% solution of NiCl |

V | MND 5.0 g・L 5% solution of NiCl | 5% solution of NiCl |

VI | MND 10.0 g・L 5% solution of NiCl | 5% solution of NiCl |

VII | 2.5% solution of K | 2.5% solution of K |

VIII | MND 5.0 g・L 2.5% solution of K | 2.5% solution of K |

IX | MND 10.0 g・L 2.5% solution of K | 2.5% solution of K |