Evaluation Item	Evaluation Results
Evaluation Item	Yes	No	Unclear	Not applicable
1) Does the study group have similar characteristics and are derived from the same research population?
2) Are the exposure factors measured in the same way and assigned to the exposed and non-exposed groups?
3) Is the evaluation method for exposure factors effective and credible?
4) Have you considered confounding factors?
5) Have you taken measures to control the confounding factors?
6) Does it describe that the study subjects do not show an observation outcome at the beginning of the exposure or study?
7) Is the evaluation method of the outcome indicator effective and credible?
8) Do you report the follow-up time and was the follow-up time long enough to observe the appearance of the outcome?