Cell types | Potential Mechanism | Effect to autophagy | References (first author, year) |
CAM | NAADP-Lysosome-Ca2+ | Positive | Zhang, 2010 |
CAM | Autophagic flux | Positive | Xu, 2011 |
Astrocytes | NAADP/TPCs, LC3-II, Beclin-1 | Positive | Pereria, 2011 |
VEC, VSMC | NAADP/TRPML1/TPCs | Positive | Li, 2013 |
MGP | LC3-II | Positive | Xiong, 2013 |
CAM | Autophagic flux | Positive | Zhang, 2014 |
CAM | Dynein ATPase | Positive | Xu, 2014 |
B cells | Blimp1, Beclin-1/p62 | Positive | Yuan, 2014 |
293T cells | NAADP/TRPML1, LRRK2/CaMKK/AMPK | Negative | Gomez-Suaga, 2012 |
CLL cells | Beclin-1, Bcl-2, Autophagic flux | Negative | Bologna, 2013 |
Hela cells, ESC | NAADP/TPC2/Ca2+ signaling, lysosomal pH | Negative | Lu, 2013 |
ESC | NAADP/TPC2/Ca2+ Signaling | Negative | Lu, 2013 |
IHP | Autophagic flux | Negative | Gomez-Puerto, 2016 |