Hemodynamic

Increased intraventricular pressure

Structural

Myocyte necrosis

Collagen matrix resolution

Intense inflammation

Traditional

Older age (>60 years)

Female sex (non-smoking woman)

Previous hypertension

First lateral or anterior wall myocardial infarction with RBBB (right bundle branch block)

No history of angina

Single vessel disease and less evidence of collateral circulation [28] [29]

Multi-vessel disease in inferior infarct rupture [30]

Steroid use and late thrombolysis (>12 - 24 hours) [31] [32] [33]