High (N = 656)

Middle (N = 1696)

Low (N = 594)

p for

trend

OR

OR(95%CI)

p value

OR(95%CI)

p value

Hypertension

No. cases

153 (23%)

577 (34%)

290 (49%)

Not adjusted

1.00 (Ref)

1.70 (1.38 to 2.09)

<0.001

3.14 (2.46 to 4.00)

<0.001

<0.001

Adjusted

1.00 (Ref)

1.25 (0.99 to 1.57)

0.06

1.71 (1.29 to 2.26)

<0.001

0.001

Diabetes

No. cases

53 (8%)

229 (14%)

112 (19%)

Not adjusted

1.00 (Ref)

1.78 (1.30 to 2.43)

<0.001

2.64 (1.87 to 3.74)

<0.001

<0.001

Adjusted

1.00 (Ref)

1.30 (0.93 to 1.81)

0.12

1.50 (1.02 to 2.20)

0.041

0.12

Hypercholesterolemia

No. cases

227 (35%)

635 (37%)

260 (44%)

Not adjusted

1.00 (Ref)

1.13 (0.94 to 1.37)

0.20

1.47 (1.17 to 1.85)

0.001

0.003

Adjusted

1.00 (Ref)

0.92 (0.76 to 1.13)

0.44

0.92 (0.72 to 1.19)

0.55

0.73

Stroke

No. cases

6 (1%)

57 (3%)

41 (7%)

Not adjusted

1.00 (Ref)

3.77 (1.62 to 8.78)

0.002

8.03 (3.38 to 19.06)

<0.001

<0.001

Adjusted

1.00 (Ref)

2.74 (1.15 to 6.50)

0.022

5.07 (2.04 to 12.60)

<0.001

0.001

Coronary heart disease

No. cases

10 (2%)

77 (5%)

28 (5%)

Not adjusted

1.00 (Ref)

3.07 (1.58 to 5.97)

0.001

3.20 (1.54 to 6.64)

0.002

0.003

Adjusted

1.00 (Ref)

2.08 (1.05 to 4.16)

0.037

1.77 (0.81 to 3.87)

0.15

0.10