Time of Drug Administration (Days) | Groups | ||||
| Group 1 (Control) | Group 2 (200 mg/kg/b.w.) | Group 3 (300 mg/kg/b.w.) | Group 4 (400 mg/kg/b.w.) | Group 5 (500 mg/kg/b.w.) |
5 | 140 ± 0.00 | 1.35 ± 0.21 | 2.05 ± 0.40 | 2.65 ± 0.35* | 2.10 ± 0.14* |
10 | 2.10 ± 0.14 | 2.70 ± 0.28* | 2.50 ± 0.41 | 2.85 ± 1.20* | 2.60 ± 0.14* |
15 | 2.20 ± 1.13 | 2.55 ± 0.21 | 2.60 ± 0.28 | 2.70 ± 0.14* | 3.30 ± 0.57* |
20 | 1.35 ± 0.07 | 2.45 ± 0.07* | 2.45 ± 0.35* | 2.35 ± 0.07* | 2.40 ± 0.14* |
28 | 2.30 ± 0.70 | 2.00 ± 0.42 | 2.35 ± 0.21* | 2.10 ± 0.14* | 2.50 ± 0.14* |