Time of Drug Administration (Days)

Groups

Group 1 (Control)

Group 2

(200 mg/kg/b.w.)

Group 3

(300 mg/kg/b.w.)

Group 4

(400 mg/kg/b.w.)

Group 5

(500 mg/kg/b.w.)

5

46.32 ± 2.38

41.50 ± 1.84*

39.20 ± 2.54*

41.17 ± 1.26*

43.14 ± 0.03*

10

42.20 ± 3.11

34.74 ± 1.75*

127.38 ± 24.3*

173.70 ± 33.23*

208.44 ± 28.61*

15

46.32 ± 2.38

138.98 ± 24.82*

104.22 ± 14.45*

146.30 ± 27.58*

181.06 ± 15.84*

20

57.90 ± 12.30

92.64 ± 20.03*

104.14 ± 21.21*

140.30 ± 27.86*

169.48 ± 14.42*

28

28.95 ± 24.56

40.53 ± 3.96*

52.11 ± 4.26*

63.69 ± 4.45*

75.27 ± 2.59*