Time of Drug Administration (Days)

Groups

Group 1 (Control)

Group 2

(200 mg/kg/b.w.)

Group 3

(300 mg/kg/b.w.)

Group 4

(400 mg/kg/b.w.)

Group 5

(500 mg/kg/b.w.)

5

118.00 ± 22.63

120.00 ± 8.49*

189.00 ± 16.9*

278.00 ± 19.8*

290.00 ± 2.83*

10

90.00 ± 2.83

159.00 ± 22.63*

160.00 ± 9.90*

189.00 ± 12.7*

196.00 ± 5.66*

15

59.00 ± 14.14

152.00 ± 26.87*

159.00 ± 7.07*

176.00 ± 5.66*

234.00 ± 19.8*

20

59.00 ± 4.24

147.00 ± 7.07*

156.00 ± 11.3*

176.00 ± 14.1*

186.00 ± 5.66*

28

76.00 ± 16.97

147.00 ± 18.39*

152.00 ± 4.24*

131.00 ± 2.83*

182.00 ± 8.49*