Authors and year | Area of research | Findings |
WHO, 2022 [19] | Fungal infections | The WHO classified 19 fungi as priority fungal pathogens and these include Cryptococcus, neoformans, Candida auris, Aspergillus fumigatus, Candida albicans, Nakaseomyces glabrata (Candida glabrata), Histoplasma spp., Eumycetoma causative agents, Mucorales, Fusarium spp., Candida tropicalis, Candida parapsilosis, Scedosporium spp., Lomentospora prolificans, Coccidioides spp., Pichia kudriavzeveii (Candida krusei), Cryptococcus gattii, Talaromyces marneffei, Pneumocystis jirovecii, and Paracoccidioides spp |
Denning, 2024 [35] | Fungal infections | Globally, over 6.5 million people suffer from invasive fungal infections annually with more than 2.1 million suffering from invasive aspergillosis, 1.8 million suffering from chronic pulmonary aspergillosis, and over 1.5 million found to have invasive candidiasis or Candida bloodstream infections. A total of 500,000 people were diagnosed with Pneumocystis pneumonia, 194,000 had Cryptococcal meningitis, and 11.5 were affected with fungal asthma. Notably, other life-threatening fungal infections caused 300,000 infections annually. Fungal infections cause approximately 3.8 million deaths annually, with over 2.5 million deaths directly attributed to fungal infections. |
Kanafani and Perfect, 2008 [90] | AFR | AFR is a global public health problem and causes an increase in morbidity and mortality, especially among high-risk populations. |
Pfaller, 2012 [91] | AFR | The overuse and misuse of antifungal agents have contributed to AFR, especially through acquired resistance, across the One Health ecology. |
Kara et al., 2021 [80] | AFS | Instigation of AFS has been demonstrated to promote rational use of antifungal agents. |
Agrawal et al., 2016 [92] | AFS | AFS is essential in addressing AFR and must be implemented in a multidisciplinary approach. |
Vitiello et al., 2023 [2] | Antifungal drug discovery | The discovery of new antifungal agents will be critical in addressing the problem of AFR. |
Vandeputte, Ferrari, and Coste, 2012 [93] | Antifungal drug discovery | The identification and discovery of new antifungal agents can contribute towards addressing AFR. |