MP formulation No.

PLGA type

Co-grinding time (min)

TDC (%)

EDC (%)

LE (%)

Particle size (μm)

7

PLGA7505

60

9.1

9.4 ± 0.0

103.6 ± 0.2

24.2 ± 9.5

8

PLGA7505

60

16.7

17.8 ± 0.0

106.5 ± 0.1

27.1 ± 13.9

9

PLGA7510

60

16.7

18.0 ± 0.4

108.1 ± 2.5

33.5 ± 5.8