Drop Seizure Frequency (per 28 days)

Placebo

EPIDIOLEX

10 mg/kg/day

EPIDIOLEX

20 mg/kg/day

Study 1

N = 85

N/A

N = 86

Baseline Period Median

75

N/A

71

Median Percentage Change During Treatment

−22

N/A

−44

p-value compared placebo

0.01

Study 2

N = 76

N = 73

N = 76

Baseline Period Median

80

87

86

Median Percentage Change During Treatment

−17

−37

−42

p-value compared placebo

<0.01

<0.01