| 
 | TROP2 | TM9SF2 | TSPAN6 | NGFR | ||||||||||||
| Area (%) | p | Score | p | Area (%) | p | Score | p | Area (%) | p | Score | p | Area (%) | p | Score | p | |
| Gender | ||||||||||||||||
| Male | 65.3 | 0.44 | 82.0 | 0.26 | 83.1 | 0.23 | 125.6 | 0.26 | 86.3 | 0.10 | 144.7 | 0.93 | 73.7 | 0.31 | 98.7 | 0.75 | 
| Female | 67.3 | 103.3 | 77.8 | 121.4 | 93.6 | 146.3 | 80.7 | 102.8 | ||||||||
| Age | ||||||||||||||||
| <65 | 66.6 | 0.36 | 103.3 | 0.15 | 82.3 | 0.86 | 131.5 | 0.19 | 85.6 | 0.24 | 141.8 | 0.69 | 80.0 | 0.29 | 106.1 | 0.30 | 
| ≥65 | 66.1 | 88.1 | 79.4 | 117.6 | 92.8 | 149.2 | 72.5 | 92.5 | ||||||||
| Location | ||||||||||||||||
| Colon | 58.0 | 0.21 | 91.0 | 0.48 | 85.4 | 0.31 | 140.9 | 0.35 | 86.2 | 0.62 | 138.7 | 0.36 | 76.8 | 0.89 | 100.0 | 0.80 | 
| Rectum | 75.3 | 97.6 | 79.3 | 116.2 | 87.7 | 138.8 | 78.0 | 102.0 | ||||||||
| Histological grade | ||||||||||||||||
| WD | 67.5 | 0.42 | 92.5 | 0.35 | 80.0 | 0.71 | 110.0 | 0.56 | 88.8 | 0.87 | 148.8 | 0.86 | 75.0 | 0.93 | 100.0 | 0.73 | 
| MD | 61.7 | 83.4 | 79.5 | 132.0 | 89.5 | 145.0 | 76.5 | 99.0 | ||||||||
| PD | 100.0 | 170.0 | 95.0 | 95.0 | 80.0 | 120.0 | 90.0 | 120.0 | ||||||||
| Stage | ||||||||||||||||
| Early | 60.8 | 0.43 | 85.0 | 0.58 | 76.8 | 0.38 | 111.8 | 0.28 | 94.4 | 0.11 | 150.0 | 0.74 | 75.2 | 0.44 | 99.0 | 0.70 | 
| Late | 70.0 | 97.7 | 85.0 | 137.1 | 86.6 | 143.3 | 81.1 | 104.4 | ||||||||
| T stage | ||||||||||||||||
| T1-T2 | 80.0 | 0.53 | 115.0 | 0.60 | 86.0 | 0.59 | 122.0 | 0.95 | 90.0 | 0.91 | 135.0 | 0.67 | 85.0 | 0.34 | 120.0 | 0.22 | 
| T3-T4 | 65.3 | 91.0 | 79.1 | 123.7 | 89.0 | 147.0 | 75.2 | 96.4 | ||||||||
| Lymph node metastasis | ||||||||||||||||
| Negative | 58.8 | 0.11 | 88.2 | 0.66 | 76.8 | 0.38 | 111.8 | 0.27 | 95.8 | 0.04 | 159.1 | 0.22 | 75.2 | 0.44 | 99.0 | 0.70 | 
| Positive | 76.1 | 98.4 | 85.0 | 137.1 | 84.4 | 136.1 | 81.1 | 104.4 | ||||||||
| CEA | ||||||||||||||||
| <5 | 61.8 | 0.41 | 81.1 | 0.38 | 77.3 | 0.51 | 112.6 | 0.36 | 89.4 | 0.93 | 148.8 | 0.67 | 72.8 | 0.35 | 95.0 | 0.50 | 
| ≥5 | 71.4 | 103.5 | 83.5 | 134.2 | 88.4 | 140.7 | 79.3 | 104.0 | ||||||||
| 5-year survival | ||||||||||||||||
| <5 | 71.6 | 0.45 | 106.6 | 0.31 | 85.0 | 0.31 | 140.0 | 0.12 | 91.7 | 0.33 | 154.7 | 0.25 | 78.3 | 0.75 | 105.8 | 0.52 | 
| ≥5 | 62.7 | 83.3 | 75.7 | 105.0 | 85.3 | 133.0 | 76.1 | 97.2 | ||||||||