IgG subclass | Type of the subclass | Variants | Amino Acids at hinge region |
IgG1 | H and L (κ and λ) chains (conventional) | IgG1a, IgG1b | IgG1a: 19 IgG1b: 12 |
IgG2 | Heavy chain Ab (HCAbs) | γ2a, γ2c | γ2a: 35 γ2c: 12 |
IgG3 | Heavy chain Ab (HCAbs) | γ3 | γ3: 15 |