| Protein | Ligand | Binding Affinity (kcal/mol) | Category | Type of Interaction | Key Interacting Residues |
| Hypothetical protein HMPREF3221_01179 | Arginine beta-naphthylamide | −7.1 | Hydrogen Bond | Conventional H bond, Pi-alkyl | Ile162, Ser166, Gln169, Asp170, Glu367, Lys433, Lys437 |