Software

Results

Retrieved SNPs

Total SNPs were 7229, 146 non-synonymous

SIFT

27 deleterious and 119 tolerated

Provean

20 deleterious and 7 neutral

Polyphen-2

17 probably damaging, 2 possibly damaging, and1 benign

SNPs & GO

14 nsSNPs had a disease association and 5 neutral

PHD SNPs

17 nsSNPs had a disease association and 2 neutral

I-Mutant

17 nsSNPs decrease the protein stability and 2increase it

MUpro

All the19 nsSNPs decrease the protein stability