Linearity of Bimatoprost

Linearity of Timolol

Concentration, (mg/ml)

Area of Bimatoprost peak

Concentration,

(mg/ml)

Area of Timolol peak

0.0060

92,352

0.1365

1,635,469

0.0096

149,498

0.2184

2,615,203

0.0120

184,672

0.2730

3,223,713

0.0144

222,385

0.3276

3,883,332

0.0180

279,656

0.4095

4,854,364

Slope

1866

Slope

32,122

Y-intercept

889.81

Y-intercept

30,221

Median (Area)

184,672

Median (Area)

3,223,713

% of Y intercept

0.48

% of Y inter

cept

0.94

Correlation coefficient, r

0.9999

Correlation coefficient, r

0.9999