TCM

Component

peak

No.

Retention

time

(min)

Compared

with

reference

substance

Content

in

medicines

(mg/g)

Ethanol

extract

Water extract

Apoptosis rate (%)*

SKOV-3

ACHN

HepG-2

Radix

angelicae

sinensis

X₁

12.43

-

0.8

3.4

0.6

5.3

5.1

0.8

7.2 → 15.3

1.2 → 4.8

2.2 → 10.9

V₁

13.416

Ligustilide

1.669

0.7

2.6

0.7

2.3

2.2

0.6

Radix

angelicae dahuricae

Y₁

6.965

-

--

--

--

2.0

--

--

7.2 → 16.5

1.2 → 8.8

2.2 → 11.7

Y₂

7.149

-

--

--

--

∞

--

--

Y₃

7.383

-

0.9

0.9

0.7

9.0

1.9

7.4

Y₄

7.496

-

1.3

0.9

0.7

12.5

2.2

7.4

Y₅

8.215

-

--

∞

--

--

--

--

Y₆

8.341

-

--

∞

--

--

--

--

C₃

8.504

Psoralen

0.028

0.9

0.8

--

4.6

--

--

Y₇

8.613

-

2.9

0.9

--

5.0

--

--

C₄

9.002

Bergapten

0.094

3.8

0.8

--

4.6

0.8

1.6

C₆

10.048

Oxypeucedanin

0.249

3.1

1.5

--

3.1

0

0.4

Y₈

10.828

-

2.9

1.3

--

--

--

--

C₇

12.341

Imperatorin

0.084

1.4

1.4

--

--

--

--

V₁

13.405

Ligustilide

0.131

1.3

--

--

--

C₈

13.939

Isoimperatorin

#

1.2

0.6

--

--

--

--

Y₉

14.668

-

2.4

∞

--

--

--

--

Fructus

Citri

sarcodactylis

C₂

6.942

Scoparone

0.169

∞

1.0

0.5

4.1

0.1

0.4

7.2 → 12.2

1.2 → 4.6

2.2 → 13.9

Z₁

7.719

-

--

0.7

--

∞

--

--

Z₂

8.208

-

--

0.9

--

1.7

--

--

Z₃

8.860

-

1.3

1.5

0.8

2.0

0.2

1.9