BMI

Mean ± SD

Fasting glucose (mg/dl)

Fasting Insulin (IU/)

HOMA β

HOMA IR

AUC

Leptin

SHBG

Testosterone

FAI

Arm A

0 month

28.3 ±6.9

83.8 ± 17.6

5.8 ± 5.8

86.3 ± 234.3

14.0 ± 22.1

209.8 ± 34.8

23.79 ± 25.62

107.41 ± 72.29

2.51 ± 2.71

4.99 ± 8.86

12 months

26.9 ±6.7

95.1 ± 32.0

4.3 ± 6.5

44.3 ± 101.1

3.8 ± 4.2

230.4 ± 29.9

24.86 ± 22.63

148.18 ± 95.14

2.85 ± 2.92

2.39 ± 2.54

P value

0.009

0.9

0.659

0.565

0.196

1

0.789

0.066

0.97

0.104

Arm B

0 month

26.7 ±4.9

82 ± 15.4

9.3 ± 15.2

257.6 ± 559.4

10.1 ± 27.6

216.7 ± 39.5

21.32 ± 16.32

82.80 ± 71.42

19.60 ± 83.82

4.31 ± 4.82

12 months

26.1 ±4.4

95.1 ± 23.7

8.3 ± 15.0

91.4 ± 160.7

4.3 ± 4.8

232.2 ± 28.8

20.89 ± 19.38

110.49 ± 76.76

3.68 ± 2.84

6.20 ± 10.49

P value

0.775

0.9

0.732

0.019

0.427

1

0.91

0.246

0.063

0.213

Arm C

0 month

27.9 ±4.9

87.2 ± 22.5

8.8 ± 14.8

53.0 ± 132.6

17.4 ± 40.3

230.7 ± 80.3

23.58 ± 17.34

88.80 ± 85.36

2.79 ± 1.82

6.29 ± 7.23

12 months

27.1 ±4.6

92.7 ± 22.8

5.5 ± 11.8

35.8 ± 52.4

11.9 ± 39.7

224.7 ± 25.1

16.44 ± 9.74

93.57 ± 82.57

2.49 ± 1.64

4.98 ±5.79

P value

0.224

0.407

0.264

0.788

0.428

0.737

0.044

0.921

0.971

0.357

Arm D

0 month

27.2 ±4.3

86.4 ± 28.5

6.8 ± 13.9

79.5 ± 239.0

5.4 ± 11.4

213.4 ± 35.0

27.70 ± 26.38

86.06 ± 70.40

2.84 ± 2.50

4.08 ± 3.41

12 months

26.8 ±3.6

98.4 ± 30.9

7.6 ± 16.4

128.8 ± 116.5

7.3 ± 23.9

223.6 ± 37.3

21.58 ± 21.57

101.78 ± 85.09

3.03 ± 2.60

4.09 ± 3.93

P value

1.000

0.019

0.777

0.416

0.768

0.737

0.073

0.511

0.98

0.996