Arm

Drugs

A

1) Cyproterone acetate (2 mg) and of Ethinylestradiol (35 microg) daily

2) Placebo pill equal to metformin daily

3) Placebo pill equal to desogestrel 0.15 mg/Ethinylestradiol (20 microg) daily

B

1) Desogestrel 0.15 mg/Ethinylestradiol (20 microg) daily

2) Placebo pill equal to metformin daily

3) Placebo pill equal to Cyproterone acetate (2 mg) and of Ethinylestradiol (35 microg) daily

C

1) Metformin 500 mg daily

2) Cyproterone acetate (2 mg) and of Ethinylestradiol (35 microg) daily

3) placebo pill equal to desogestrel 0.15 mg/Ethinylestradiol (20 microg) daily

D

1) Metformin 500 mg daily

2) Desogestrel 0.15 mg/Ethinylestradiol (20 microg) daily

3) Placebo pill equal to Cyproterone acetate (2 mg) and of Ethinylestradiol (35 microg) pill daily