Control Subjects

Patients

p^†

N

10

36

Duration exercise (min)

11.4 ± 2.4

Vt (L)

2.02 ± 0.58

1.52 ± 0.56

0.05

Respir rate (breaths/min)

39.4 ± 5.8

37.3 ± 9.6

NS

V’_E (L/min)

78.8 ± 23.6

52.2 ± 16.7

0.01

V’_E/MVV (%)

58.3 ± 10.4

58 ± 15.4

NS

V’O₂ (mL/min)

2003 ± 790

1145 ± 373

<0.001

V’O₂ (% pred)

93.9 ± 11.8

64.6 ± 18.9

<0.01

V’O₂/HR (mL/beat)

13.6 ± 4.9

9.1 ± 3

0.02

V’O₂/HR (% pred)

108.7 ± 16.7

60.2 ± 11

<0.001

V’_E/V’O₂ (%)

41.5 ± 9.5

46.8 ± 11.4

0.05

V’_E/V’O₂ (% pred)

89.5 ± 17.2

135.9 ± 56

<0.01

V’CO₂ (mL/min)

2469 ± 871

1344 ± 546

0.005

RER

1.25 ± 0.1

1.17 ± 0.1

<0.02

V’_E/V’CO₂ (%)

33 ± 5.8

39.3 ± 8.3

<0.02

V’_E/V’CO₂ (% pred)

86.3 ± 12.7

139.1 ± 58.9

<0.001

Slope V’_E/V’CO₂**

32.3 ± 5.9

37.9 ± 9.2

<0.05

Intercept V’_E (L/min)**

1.45 ± 1.5

1.95 ± 2.98

NS