Lung Volume Subdivisions

MMRC

0

(n = 76)

2

(n = 147)

4

(n = 108)

P-value†

FVC, liters

3.6 ± 1.1

3.2 ± 1.0

2.6 ± 0.9

0.002

FVC, % pred

93.6 ± 19.6

87.5 ± 19.2

73.8 ± 22.6

<0.001

SVC, liters

3.8 ± 1.0

3.3 ± 1.1

2.9 ± 0.9

0.009

SVC, % pred

100.0 ± 18.6

90.9 ± 20.1

79.9 ± 19.6

<0.001

FEV1, liters

2.1 ± 0.7

1.8 ± 0.7

1.5 ± 0.7

0.005

FEV1, % pred

77.5 ± 19.9

67.5 ± 22.1

56.6 ± 24.1

0.01

FEV1/FVC

0.60 ± 0.09

0.55 ± 0.13

0.54 ± 0.11

<0.001

TLC, liters

6.1 ± 1.2

6.1 ± 1.5

5.6 ± 1.5

<0.001

TLC, % pred

104.9 ± 21.4

110.4 ± 18.3

103.2 ± 20.7

<0.001

FRC, liters

3.6 ± 0.8

3.8 ± 1.1

3.7 ± 1.3

<0.001

FRC, % pred

113.7 ± 24.7

122.0 ± 30.3

121.1 ± 35.7

<0.001

RV, liters

2.5 ± 0.8

2.9 ± 1.1

2.9 ± 1.2

<0.001

RV, % pred

126.3 ± 37.6

151.9 ± 50.6

157.2 ± 57.6

<0.001

IC, liters

2.5 ± 0.8

2.4 ± 0.8

1.9 ± 0.7

<0.001

IC, % pred

96.1 ± 23.8

95.4 ± 22.9

80.6 ± 25.2

<0.001

IC/SVC

0.67 ± 0.11

0.73 ± 0.12

0.71 ± 0.14

<0.001

IC/TLC

0.40 ± 0.07

0.39 ± 0.09

0.35 ± 0.10

<0.001

FRC/TLC

0.60 ± 0.07

0.61 ± 0.09

0.65 ± 0.10

<0.001

RV/TLC

0.41 ± 0.10

0.47 ± 0.11

0.51 ± 0.12

<0.001

SVC/FVC

1.02 ± 0.06

1.02 ± 0.11

1.03 ± 0.08

<0.001