Dataset ID

Normalization Method

Quality Control Metrics

Data Integrity Notes

DS1

Quantile normalization

Signal-to-noise ratio, background correction

No outliers were detected; the data was within the expected range.

DS2

RMA (Robust Multi-array Average)

Control probe performance, missing value counts

Missing values are imputed with k-nearest neighbors.

DS3

Loess normalization

Intensity distribution, spatial artifacts

Data adjusted for spatial heterogeneity.

DS4

Scaling normalization

Coefficient of variation, batch effects

Batch correction was applied using the ComBat algorithm.