| large TKV (n = 9) | small TKV (n = 9) | ||
| RPF (ml/min) | - tolvaptan | 594 ± 268 | 713 ± 204 |
| - placebo | 572 ± 217 | 729 ± 177 | |
| GFR (ml/min) | - tolvaptan | 64 ± 17 | 92 ± 27# |
| - placebo | 67 ± 14 | 90 ± 21 | |
| FF (%) | - tolvaptan | 13 ± 5 | 13 ± 3 |
| - placebo | 13 ± 4 | 13 ± 4 | |