| Induction therapy |
| DOSE | Comments |
| Methylprednisolone then prednisolone | IV PO | MP 500 - 750 mg × 3 days then prednisone 0.5 - 1 mg/kg/day to a maximum of 60 mg tapered after a few weeks to lowest effective dose | Usually 3 - 6 months |
|
| Plus |
| |
| MPS-First option | PO | 720 - 1080 mg twice daily | |
| IV Cyclophosphamide Second option | IV | 500 mg IV once in 2 weeks ×6 | Cannot tolerate or not responding to MPS |
| Maintenance Therapy | Plus |
|
|
| Prednisolone | PO | slow tapering dose to 5 - 7 mg | Usually 18 months since remission |
| MPS or MMF-First option | PO | MPS-720 mg twice daily/MMF 1 gm bid | |
| Azathioprine-Second Option | PO | 1 - 2 mg/kg/day | |
|
|
| Plus | |
| Hydroxychloroquine | PO | 400 mg daily |