Variable | Isolated Valve Surgery (IVS) | Valve Surgery + CABG (VS + CABG ) | p-value |
n = 1608 | n = 59 |
| |
Age (years) | 44.4 ± 13.1 | 64.9 ± 9.2 | <0.001 |
Gender F/M | 48%/52% | 19%/81% | <0.001 |
Diabetes mellitus | 6.6% (n = 107) | 40.7% (n = 24) | <0.001 |
Arterial hypertension | 9.2% (n = 148) | 35.6% (n = 21) | <0.001 |
Dyslipidemia | 6.4% (n = 103) | 30.5% (n = 18) | <0.001 |
Tabacco use | 25.0% (n = 402) | 49.1% (n = 29) | <0.001 |
Chronic obstructive pulmonary disease | 4.2% (n = 69) | 6.7% (n = 4) | NS |
Renal failure | 5.1% (n = 83) | 5.0% (n = 3) | NS |
Stroke | 5.2% (n = 84) | 1.6% (n = 1) | NS |
Euroscore | 2.49 ± 2.6 | 5.64 ± 2.6 | <0.001 |
Logistic euroscore | 3.34 ± 6.0 | 6.1 ± 5.9 | 0.001 |
Cardiovascular risk factors | 0.60 ± 0.83 | 1.73 ± 1.11 | <0.001 |
BMI (Kg/m2) | 24.2 ± 4.7 | 25.9 ± 2.7 | 0.004 |
CCSIII | 0.7% (n = 10) | 5.2% (n = 3) | 0.013 |
Dyspnea NYHA III-IV | 59.7% (n = 960) | 38.9% (n = 23) | 0.002 |
Cardiac heart failure | 9.8% (n = 158) | 3.4% (n = 2) | NS |
Sinus rhythm | 57.4% (n = 923) | 88.1% (n = 52) | <0.001 |
Atrial fibrillation | 42.6% (n = 685) | 11.9% (n = 7) | <0.001 |
Cardio thoracic index | 0.57 ± 0.07 | 0.55 ± 0.06 | 0.028 |
Echocardiographic findings: |
|
|
|
Left atrium diameter (mm) | 53.1 ± 11.2 | 43,5 ± 6.9 | <0.001 |
ESLVD (mm) | 38.8 ± 10.3 | 39.4 ± 9.3 | 0.69 |
EDLVD (mm) | 56.8 ± 11.5 | 57.7 ± 10.2 | 0.57 |
LVEF (%) | 58.0 ± 11.2 | 52.8 ± 13.7 | 0.001 |
Low left ventricle ejection fraction (<40%) | 9.5% (n = 154) | 30.5% (n = 18) | <0.001 |
PASP (mmHg) | 50.8 ± 18.8 | 45.1 ± 17.0 | 0.11 |
Pre-operative blood tests |
|
|
|
Hemoglobine (g/dl) | 13.3 ± 1.9 | 13.6 ± 1.3 | 0.24 |
Uree (g/l) | 0.41 ± 0.24 | 0.44 ± 0.16 | 0.30 |
Creatinine (mg/l) | 10.0 ± 5.5 | 10.7 ± 3.3 | 0.36 |
Platelets count (×103/mm3) | 225.1 ± 69.3 | 199.1 ± 55.2 | 0.008 |