All, N = 333

SILB, N = 207

ISCC, N = 126

P-Value^a

Day 0—No meds

13 (4)

13 (6)

0 (0)

0.001

Day 0—Non Opioids Only

68 (20)

35 (17)

33 (26)

Day 0—Opioids Only

228 (68)

148 (71)

80 (63)

Day 0—Both

24 (7)

11 (5)

13 (10)

All, N = 329

SILB, N = 203

ISCC, N = 126

P-Value^a

Day 1—No meds

11 (3)

11 (5)

0 (0)

0.014

Day 1—Non Opioids Only

30 (9)

16 (8)

14 (11)

Day 1—Opioids Only

195 (59)

124 (61)

71 (56)

Day 1—Both

93 (28)

52 (26)

41 (33)

All, N = 116

SILB, N = 70

ISCC, N = 46

P-Value^a

Day 2—No meds

2 (2)

2 (3)

0 (0)

0.523

Day 2—Non Opioids Only

5 (4)

3 (4)

2 (4)

Day 2—Opioids Only

59 (51)

38 (54)

21 (46)

Day 2—Both

50 (43)

27 (39)

23 (50)

All, N = 54

SILB, N = 32

ISCC, N = 22

P-Value^a

Day 3—No meds

1 (2)

1 (3)

0 (0)

0.025

Day 3—Non Opioids Only

7 (13)

7 (22)

0 (0)

Day 3—Opioids Only

19 (35)

12 (38)

7 (32)

Day 3—Both

27 (50)

12 (38)

15 (68)

All, N = 30

SILB, N = 26

ISCC, N = 14

P-Value^a

Day 4—Non Opioids Only

3 (10)

2 (13)

1 (7)

0.217

Day 4—Opioids Only

11 (37)

8 (50)

3 (21)

Day 4—Both

16 (53)

6 (38)

10 (71)

All, N = 22

SILB, N = 12

ISCC, N = 10

P-Value^a

Day 5—Non Opioids Only

3 (14)

2 (17)

1 (10)

0.107

Day 5—Opioids Only

9 (41)

7 (58)

2 (20)

Day 5—Both

10 (45)

3 (25)

7 (70)