Group L* (n = 27)

Group K^† (n = 28)

Group KL^‡ (n = 29)

Group P^§ (n = 29)

P value

N/V^#

0.6 (0.9)

10 (37%)

0.9 (2.0)

10 (35.7%)

0.3 (0.6)

8 (27.6%)

0.9 (1.1)

14 (48.3%)

0.72

Pruritus

0.8 (1.1)

10 (37%)

0.9 (1.2)

13 (46.4%)

0.7 (1.0)

11 (37.9%)

0.8 (0.8)

16 (55.2%)

0.12

Lightheadedness

0.4 (0.6)

10 (37%)

0.5 (0.8)

11 (39.3%)

0.7 (0.9)

13 (44.8%)

0.6 (0.6)

14 (48.3%)

0.73

Oral numbness

0.0 (0.2)

1 (3.7%)

0.1 (0.4)

2 (7.1%)

0.1 (0.3)

2 (6.9%)

0.0 (0.0)

0 (0%)

0.53

Hallucinations

0.4 (0.7)

7 (25.9%)

0.3 (0.6)

6 (21.4%)

0.5 (0.8)

10 (34.5%)

0.4 (0.9)

6 (20.7%)

0.85