Midazolam group (N = 50)

Control group

(N = 50)

P-value

Mean ± SD

Mean ± SD

Basal (preoperative)

160.6 ± 13.3#

164.07 ± 17.4#

0.264

Before induction

148.6 ± 7.0#

150.7 ± 10.7#

0.230

After induction

134.4 ± 8.1#

129.4 ± 14.05#

0.032*

5 minutes

124.4 ± 11.6#

116.07 ± 20#

0.012*

10 minutes

120.9 ± 10.9#

111.7 ± 18.7#

0.004*

After delivery of placenta

116.2 ± 10.4#

107.4 ± 15.9#

0.002*

10 minutes

118.0 ± 9.03#

116.4 ± 16.9#

0.574

20 minutes

120.0 ± 8.08#

125.09 ± 15.6#

0.043*

30 minutes

120.6 ± 7.9#

127.4 ± 16.1#

0.008*

10 minutes Postoperative

127.8 ± 12.0#

135.8 ± 15.6#

0.004*

30 minutes Postoperative

130.6 ± 12.5#

138.03 ± 14.6#

0.007*

One hour Postoperative

129.4 ± 12.5#

138.8 ± 13.6#

<0.001*

Four hours Postoperative

133.0 ± 12.4#

144.9 ± 14.8#

<0.001*

Six hours Postoperative

134.4 ± 14.02#

148.4 ± 14.7#

<0.001*

Twelve hours Postoperative

129.1 ± 27.4#

148.8 ± 14.7#

<0.001*

Eighteen hours Postoperative

134.6 ± 15.5#

145.8 ± 14.8#

<0.001*

Twenty-four hours Postoperative

131.8 ± 15.3#

146.2 ± 16.1#

<0.001*