Time | (p) group (n = 22) | (L) group (n = 22) | (G) group (n = 22) | (LG) group) (n = 22) | P value |

Before induction | 84.5 ± 17.6 | 86.4 ± 16.5 | 85.8 ± 16.7 | 82.2 ± 15.6 | 0.834 |

After intubation | 101.4 ± 12.5 | 90.2 ± 7.8 | 90.6 ± 6.7 | 89.4 ± 9.5 | <0.001 |

After 15 min | 98.4 ± 10.9 | 87.6 ± 7.8 | 86.7 ± 6.9 | 86.5 ± 7.1 | <0.001 |

After 30 min | 90.6 ± 8.7 | 87.7 ± 7.9 | 88.4 ± 8.2 | 87.9 ± 8.4 | 0.638 |

After 45 min | 89.4 ± 8.7 | 86.5 ± 8.2 | 87.7 ± 8.4 | 85.8 ± 8.8 | 0.525 |

After 60 min | 88.8 ± 7.6 | 86.7 ± 7.4 | 89.6 ± 8.2 | 85.9 ± 7.9 | 0.355 |

Aftern 75 min | 92.3 ± 8.8 | 91.4. ± 7.8 | 90.1 ± 7.9 | 90.2 ± 7.8 | 0.775 |

After 90 min | 90.7 ± 9.9 | 88.6 ± 8.2 | 87.3 ± 8.4 | 89.4 ± 8.6 | 0.631 |

At end of surgery | 93.6 ± 7.7 | 90,7 ± 8.9 | 91.4 ± 8.4 | 89.4 ± 8.2 | 0.404 |