| Pharmacokinetic parameter | Midazolam | Midazolam and acetaminophen | p value |
| Maximal concentration (Cmax) (ng/ml) | 247 ± 258 | 242 ± 126 | 0.45 |
| Time to maximal concentration (Tmax) (min) | 92 ± 31 | 91 ± 31 | 0.44 |
| Time to half decline in concentration (t1/2) (min) | 166 ± 60 | 195 ± 63 | 0.07 |
| Area under the curve (AUC) (g-min/ml) | 93 ± 99 | 85 ± 64 | 0.24 |
| Rate of clearance (ml/min/kg) | 4.8 ± 2.1 | 4.5 ± 1.7 | 0.67 |