Characteristics

Age

47 years

Clinical history

· Chronic smoking weaned

· followed since 2014 for Crohn’s disease with ano-perineal manifestations

Admitted for

Sensitive neuropathy

Current treatment

Combotherapy (infliximab, 6-mercapthopurine)

Clinical

· dysesthesia

· painful cramps

Physical examination

· no fever

· Digital rectal: very painful, sphincteric hypotonia

· Hypoesthesia in sock reaching the ankles on